I don't think many would have pegged this as one of the top films coming out this month, but it's been a really sad and depressing year for comedies. There's a bit of irony in that the one with most depressing subject matter has the most potential. Honestly, I keep hearing about people getting illogically excited for "What's Your Number?" and I'm wondering why that energy isn't being pointed towards "50/50". This isn't an insensitive sort of film, and there's some kind of honesty going on here. It's based on the writer and Seth Rogen's experience of this. There's got to be some honesty in the pot.